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Summary
Quarter-final 1
| Rank | Name | Nation | Time |
| 1 | Carl Lewis | USA | 20.57 |
| 2 | John Regis | GBR | 20.61 |
| 3 | Cyprian Enweani | CAN | 20.62 |
| 4 | Edgardo Guilbe | PUR | 20.73 |
| 5 | Kenji Yamauchi | JPN | 20.94 |
| 6 | Jimmy Flemming | ISV | 21.23 |
| 7 | Mustafa Kamel Selmi | ALG | 21.26 |
| 8 | Ousmane Diarra | MLI | 21.46 |
| Rank | Name | Nation | Time |
| 1 | Bruno Marie-Rose | FRA | 20.48 |
| 2 | Roy Martin | USA | 20.54 |
| 3 | Troy Douglas | BER | 20.70 |
| 4 | Kennedy Ondiek | KEN | 20.79 |
| 5 | Attila Kovacs | HUN | 21.19 |
| 6 | Lee Shiunn-Long | TPE | 21.34 |
| 7 | Harouna Pale | BUR | 21.35 |
| Did not start | |||
| Pietro Mennea | ITA | ||
| Rank | Name | Nation | Time |
| 1 | Linford Christie | GBR | 20.49 |
| 2 | Atlee Mahorn | CAN | 20.59 |
| 3 | Ralf Lubke | FRG | 20.80 |
| 4 | Luis Barroso | POR | 20.81 |
| 5 | Patrick Stevens | BEL | 20.94 |
| 6 | John Myles-Mills | GHA | 20.95 |
| 7 | Andreas Berger | AUT | 21.40 |
| 8 | Ibrahim Tamba | SEN | 21.93 |
| Rank | Name | Nation | Time |
| 1 | Joe Deloach | USA | 20.56 |
| 2 | Gilles Queneherve | FRA | 20.77 |
| 3 | Olapade Adeniken | NGR | 20.92 |
| 4 | Norbert Dobeleit | FRG | 20.98 |
| 5 | Mark Garner | AUS | 21.08 |
| 6 | Chang Jae-Keun | KOR | 21.35 |
| 7 | Li Feng | CHN | 21.38 |
| 8 | Oliver Daniels | LBR | 22.25 |
| Rank | Name | Nation | Time |
| 1 | Robson da Silva | BRA | 20.41 |
| 2 | Stefano Tilli | ITA | 20.67 |
| 3 | Michael Rosswess | GBR | 20.74 |
| 4 | Clive Wright | JAM | 20.81 |
| 4 | Daniel Sangouma | FRA | 20.81 |
| 6 | Isiaq Adeyanju | NGR | 21.01 |
| 7 | Courtney Brown | CAN | 21.18 |
| 8 | Samuel Nchinda-Kaya | CMR | 21.39 |