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Summary
| Rank | Name | Nation | Time |
| 1 | Florence Griffith Joyner | USA | 10.54 |
| 2 | Evelyn Ashford | USA | 10.83 |
| 3 | Heike Drechsler | GDR | 10.85 |
| 4 | Grace Jackson | JAM | 10.97 |
| 5 | Gwen Torrence | USA | 10.97 |
| 6 | Natalia Pomochtchnikova | URS | 11.00 |
| 7 | Juliet Cuthbert | JAM | 11.26 |
| 8 | Anelia Vetchernikova | BUL | 11.49 |