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Date: 15 August 2010
Summary
Final 1
| Rank | Name | Nation | Time |
| 1 | Sun Bowei; Tang Yi; Liu Lan; He Jianbin | CHN | 3:31.34 |
| 2 | Kenneth To; Emma McKeon; Madison Wilson; Justin James | AUS | 3:31.69 |
| 3 | Medhy Metella; Anna Santamans; Mathilde Cini; Jordan Coelho | FRA | 3:35.90 |
| 4 | Chad Bobrosky; Lauren Earp; Lindsay Delmar; Jeremy Bagshaw | CAN | 3:36.05 |
| 5 | Melvin Herrmann; Lina Rathsack; Juliane Reinhold; Kevin Leithold | GER | 3:36.06 |
| 6 | Erich Peske; Kiera Janzen; Jordan Mattern; Thomas Stephens | USA | 3:39.08 |
| 7 | Ching Tat Lum; Kin Tat Kent Cheung; Wai Ting Yu; Yvette Man-Yi Kong | HKG | 3:40.08 |
| 8 | Andrey Ushakov; Kristina Kochetkova; Ekaterina Andreeva; Alexey Atsapkin | RUS | 3:42.63 |