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Summary
| Rank | Name | Nation | Time |
| 1 | Dawn Harper | USA | 12.54 |
| 2 | Sally McLellan | AUS | 12.64 |
| 3 | Priscilla Lopes-Schliep | CAN | 12.64 |
| 4 | Damu Cherry | USA | 12.65 |
| 5 | Delloreen Ennis-London | JAM | 12.65 |
| 6 | Brigitte Foster-Hylton | JAM | 12.66 |
| 7 | Lolo Jones | USA | 12.72 |
| 8 | Sarah Claxton | GBR | 12.94 |