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Summary
| Rank | Name | Nation | Time |
| 1 | Felix Sanchez | DOM | 47.63 |
| 2 | Danny McFarlane | JAM | 48.11 |
| 3 | Naman Keita | FRA | 48.26 |
| 4 | James Carter | USA | 48.58 |
| 5 | Bayano Kamani | PAN | 48.74 |
| 6 | Marek Plawgo | POL | 49.00 |
| 7 | Alwyn Myburgh | RSA | 49.07 |
| 8 | Bennie Brazell | USA | 49.51 |