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Date: 27 July 1980 / 28 July 1980
Heats
Semi-finals
Final
| Rank | Name | Nation | Time |
| 1 | Vera Komisova | URS | 12.56 |
| 2 | Johanna Klier | GDR | 12.63 |
| 3 | Lucyna Langer | POL | 12.65 |
| 4 | Kerstin Claus | GDR | 12.66 |
| 5 | Grazyna Rabsztyn | POL | 12.74 |
| 6 | Irina Litovchenko | URS | 12.84 |
| 7 | Bettine Gartz | GDR | 12.93 |
| 8 | Zofia Bielczyk | POL | 13.08 |
| Semi-finals | |||
| 9 | Shirley Strong | GBR | 13.12 |
| 10 | Laurence Elloy | FRA | 13.33 |
| 11 | Yordanka Donkova | BUL | 13.39 |
| 12 | Laurence Le Beau | FRA | 13.54 |
| 13 | Helena Pihl | SWE | 13.68 |
| 14 | Daniela Valkova | BUL | 13.79 |
| 15 | Xenia Siska | HUN | |
| 16 | Tatiana Anisimova | URS | |
| Heats | |||
| 17 | Penelope Gillies | AUS | 13.68 |
| 18 | Lorna Boothe | GBR | 13.86 |
| 19 | Marisela Peralta | DOM | 14.18 |
| 20 | Estella Meheux | SLE | 15.61 |
| Did not start | |||
| Nancy Vallecilla | ECU | ||
| Yvonne Von Kauffungen | SUI | ||