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Date: 3 September 1972
Summary
Final 1
| Rank | Name | Nation | Time |
| 1 | Mark Spitz | USA | 51.22 |
| 2 | Jerry Heidenreich | USA | 51.65 |
| 3 | Vladimir Bure | URS | 51.77 |
| 4 | John Murphy | USA | 52.08 |
| 5 | Michael Wenden | AUS | 52.41 |
| 6 | Igor Grivennikov | URS | 52.44 |
| 7 | Michel Rousseau | FRA | 52.90 |
| 8 | Klaus Steinbach | FRG | 52.92 |